Pelakon utama

• Angel Locsin as Monica "Ikay" Santiago-de Villa
• Jericho Rosales as Adrian de Villa
• Maja Salvador as Nicole Esquivel
• JC de Vera as Max Gonzales

Pelakon pembantu

• Christopher de Leon as Javier Santiago, Sr.
• Rio Locsin as Eloisa Santiago
• Mark Gil as Dante Ramos
• Maria Isabel Lopez as Sandra de Villa
• Joem Bascon as Javier "Javi" Santiago. Jr.
• Ahron Villena as Jasper Santiago
• Janus del Prado as Bradley
• Matet de Leon as Rowena

Pelakon pembantu khas

• Bernard Palanca as Miguel Zapanta
• Vandolph Quizon as Samboy
• Joe Vargas as Andrew de Villa
• Pamu Pamorada as Trish de Villa
• Odette Khan as Yaya Krising
• Leo Rialp as Eduardo "Gramps" Esquivel
• Pinky Marquez as Emma Alvaro
• Michael Flores as Bob Rivera
• Thou Reyes as Jon
• Dionne Monsanto as Rhea
• Zeppi Borromeo as Anton
• Carla Humphries as Audrey
• Johan Santos as Vincent "Vince" Madriaga
• Jesse James Ongteco / Yogo Singh as Javier "Thirdy" Santiago III
• Frenchie Dy as Kelly
• Sonjia Calit as Gwen Santiago

Pelakon undangan

• Bugoy Cariño as young Jasper
• Casey De Silvia as young Nicole
• Xyriel Manabat as young Monica
• Aaron Junatas as young Javi
• James Blanco as young Javier
• Neri Naig as young Eloisa
• Matt Evans as young Dante
• Dang Cruz as young Yaya Krising
• Junjun Nayra as Atty. Hector Vargas/Monica's Lawyer
• Ricardo Cepeda as Manuel Gonzales/Max's Dad
• Carlos Morales as Javier De Villa