Tan Sri Dato' Hj Othman Mustapha bersekolah di Ma'ahad Muhammadi ,Kota Bharu, Kelantan.

Beliau memperoleh Ijazah Sarjana Muda (Kepujian) Pengajian Islam (Syariah) UKM (1982), Certificate of Special Course For Malaysia Islamic Officers 2010, London, Certificate of Sharia Governance Course 2007, Birmingham University, UK.