The city has one professional football club, Bursaspor, which competes in the Turkish Super League, the top-tier of Turkish football. Bursaspor has won its first league title in the 2009–10 Turkish Super League season, becoming the second Anatolian club to ever win the league title after Trabzonspor. Bursaspor is today considered one of the five biggest football clubs in Turkey along with Galatasaray, Fenerbahçe, Beşiktaş and Trabzonspor.

The city had a professional basketball team in the Turkish Basketball League, Tofaş S.K., which was among the most successful teams; until it stopped participating in the league following a decision by the automobile manufacturer Tofaş, its sponsor and parent company.